Decision making and quality of life in the treatment of cancer: a review.


Journal Article (Review)

INTRODUCTION: Complexity in decision making for cancer treatment arises from many factors. When considering how to treat patients, physicians prioritize factors such as stage of disease, patient age, and comorbid illnesses. However, physicians must balance these priorities with the patient's preferences, quality of life, social responsibilities, and fear of uncertainty. Although these factors are important, physicians are often unable to effectively judge their patients' preferences. Patients are often unable to fully understand their prognoses and the treatment intent. DISCUSSION: These differences influence how patients and physicians make treatment-related decisions. Partially due to these differences, patients are initially more likely than their physicians to accept greater risk for lesser benefit from treatment. As time progresses and as they experience treatment, a patient's preference changes, yet little is known about this process since few studies have examined it in a prospective longitudinal manner. We present an overview of the literature related to patient and physician decision making and quality of life in patients with advanced cancer, and we propose approaches to future decision-making models in cancer treatment.

Full Text

Duke Authors

Cited Authors

  • Zafar, SY; Alexander, SC; Weinfurt, KP; Schulman, KA; Abernethy, AP

Published Date

  • February 2009

Published In

Volume / Issue

  • 17 / 2

Start / End Page

  • 117 - 127

PubMed ID

  • 18802727

Pubmed Central ID

  • 18802727

International Standard Serial Number (ISSN)

  • 0941-4355

Digital Object Identifier (DOI)

  • 10.1007/s00520-008-0505-2


  • eng

Conference Location

  • Germany