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Intraurethral activation of excitatory bladder reflexes in persons with spinal cord injury.

Publication ,  Journal Article
Yoo, PB; Horvath, EE; Amundsen, CL; Webster, GD; Grill, WM
Published in: Annu Int Conf IEEE Eng Med Biol Soc
2009

Electrical activation of an excitatory reflex between sensory fibers in the pudendal nerve and the bladder has been demonstrated in cats and is a potential means of restoring micturition function in persons with spinal cord injury. We investigated the clinical feasibility of activating this reflex to restore bladder function in persons with spinal cord injury by using intraurethral electrical stimulation to activate pudendal sensory fibers innervating the urethra. Excitatory bladder responses (contractions) were evoked by trains of electrical pulses applied to either the proximal (29.7 +/- 11.6 cmH2O) or distal (30.2 +/- 11.6 cmH2O) segment of the urethra. The results indicate that an excitatory reflex between pudendal nerve afferents and the bladder exists in humans with spinal injury and may provide a substrate for restoring micturition function.

Duke Scholars

Published In

Annu Int Conf IEEE Eng Med Biol Soc

DOI

ISSN

2375-7477

Publication Date

2009

Volume

2009

Start / End Page

6781 / 6784

Location

United States

Related Subject Headings

  • Urodynamics
  • Urinary Bladder
  • Urethra
  • Spinal Cord Injuries
  • Reflex
  • Middle Aged
  • Male
  • Humans
  • Female
  • Electromyography
 

Citation

APA
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ICMJE
MLA
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Yoo, P. B., Horvath, E. E., Amundsen, C. L., Webster, G. D., & Grill, W. M. (2009). Intraurethral activation of excitatory bladder reflexes in persons with spinal cord injury. Annu Int Conf IEEE Eng Med Biol Soc, 2009, 6781–6784. https://doi.org/10.1109/IEMBS.2009.5333982
Yoo, Paul B., Eric E. Horvath, Cindy L. Amundsen, George D. Webster, and Warren M. Grill. “Intraurethral activation of excitatory bladder reflexes in persons with spinal cord injury.Annu Int Conf IEEE Eng Med Biol Soc 2009 (2009): 6781–84. https://doi.org/10.1109/IEMBS.2009.5333982.
Yoo PB, Horvath EE, Amundsen CL, Webster GD, Grill WM. Intraurethral activation of excitatory bladder reflexes in persons with spinal cord injury. Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:6781–4.
Yoo, Paul B., et al. “Intraurethral activation of excitatory bladder reflexes in persons with spinal cord injury.Annu Int Conf IEEE Eng Med Biol Soc, vol. 2009, 2009, pp. 6781–84. Pubmed, doi:10.1109/IEMBS.2009.5333982.
Yoo PB, Horvath EE, Amundsen CL, Webster GD, Grill WM. Intraurethral activation of excitatory bladder reflexes in persons with spinal cord injury. Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:6781–6784.

Published In

Annu Int Conf IEEE Eng Med Biol Soc

DOI

ISSN

2375-7477

Publication Date

2009

Volume

2009

Start / End Page

6781 / 6784

Location

United States

Related Subject Headings

  • Urodynamics
  • Urinary Bladder
  • Urethra
  • Spinal Cord Injuries
  • Reflex
  • Middle Aged
  • Male
  • Humans
  • Female
  • Electromyography