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A historical perspective on the discovery of adenyl purines.

Publication ,  Journal Article
Cheek, DJ; McHugh, JM; Blood-Siegfried, J; McFetridge, JF; Turner, BS
Published in: Biological research for nursing
April 2000

In 1929, Drury and Szent-Gyorgyi described the effects of a simple extract of heart muscle and other tissues on the mammalian heart. This extract was identified as adenylic acid and found to have profound effects on the cardiovascular system. The discovery and identification of adenyl purines and their effects on the cardiovascular system has now extended to other biological functions such as neurotransmission, neuromodulation, and endocrine/exocrine secretory functions and beyond. This review examines the history of the discovery and identification of the many roles played by adenyl purines in regulation of physiological homeostasis.

Duke Scholars

Published In

Biological research for nursing

DOI

EISSN

1552-4175

ISSN

1099-8004

Publication Date

April 2000

Volume

1

Issue

4

Start / End Page

265 / 275

Related Subject Headings

  • Signal Transduction
  • Physiology
  • Nursing
  • Neurotransmitter Agents
  • Myocardium
  • Humans
  • Homeostasis
  • History, 20th Century
  • Cardiovascular System
  • Animals
 

Citation

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ICMJE
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Cheek, D. J., McHugh, J. M., Blood-Siegfried, J., McFetridge, J. F., & Turner, B. S. (2000). A historical perspective on the discovery of adenyl purines. Biological Research for Nursing, 1(4), 265–275. https://doi.org/10.1177/109980040000100403
Cheek, D. J., J. M. McHugh, J. Blood-Siegfried, J. F. McFetridge, and B. S. Turner. “A historical perspective on the discovery of adenyl purines.Biological Research for Nursing 1, no. 4 (April 2000): 265–75. https://doi.org/10.1177/109980040000100403.
Cheek DJ, McHugh JM, Blood-Siegfried J, McFetridge JF, Turner BS. A historical perspective on the discovery of adenyl purines. Biological research for nursing. 2000 Apr;1(4):265–75.
Cheek, D. J., et al. “A historical perspective on the discovery of adenyl purines.Biological Research for Nursing, vol. 1, no. 4, Apr. 2000, pp. 265–75. Epmc, doi:10.1177/109980040000100403.
Cheek DJ, McHugh JM, Blood-Siegfried J, McFetridge JF, Turner BS. A historical perspective on the discovery of adenyl purines. Biological research for nursing. 2000 Apr;1(4):265–275.
Journal cover image

Published In

Biological research for nursing

DOI

EISSN

1552-4175

ISSN

1099-8004

Publication Date

April 2000

Volume

1

Issue

4

Start / End Page

265 / 275

Related Subject Headings

  • Signal Transduction
  • Physiology
  • Nursing
  • Neurotransmitter Agents
  • Myocardium
  • Humans
  • Homeostasis
  • History, 20th Century
  • Cardiovascular System
  • Animals