Subarachnoid Techniques for Cancer Pain Therapy: When, Why, and How?


Journal Article

For cancer patients who obtain inadequate pain relief with conservative treatment, there is a growing list of effective options for subarachnoid therapy. Morphine and bupivacaine have been the most frequently used drugs for intrathecal infusion, and their use has consistently yielded good results. Despite their effectiveness, however, a therapeutic deficit remains, primarily in the treatment of neuropathic cancer pain. Because of this limitation, more recent research has focused on novel compounds for intrathecal therapy such as clonidine, midazolam, ketamine, and SNX-111. In addition to new drug options, there are various catheter delivery systems from which to choose. In reviewing the literature and experience to date with these various medications and delivery systems, we hope to better aid the clinician in tailoring the best treatment for each patient.

Full Text

Duke Authors

Cited Authors

  • Buchheit, T; Rauck, R

Published Date

  • 1999

Published In

Volume / Issue

  • 3 / 3

Start / End Page

  • 198 - 205

PubMed ID

  • 10998675

Pubmed Central ID

  • 10998675

International Standard Serial Number (ISSN)

  • 1069-5850


  • eng

Conference Location

  • United States