Part II. Analysis of data gaps pertaining to Shigella infections in low and medium human development index countries, 1984-2005.

Journal Article (Journal Article;Review)

The global incidence of Shigella infection has been estimated at 80-165 million episodes annually, with 99% of episodes occurring in the developing world. To identify contemporary gaps in the understanding of the global epidemiology of shigellosis, we conducted a review of the English-language scientific literature from 1984 to 2005, restricting the search to low and medium human development countries. Our review yielded 11 population-based studies of Shigella burden from seven countries. No population-based studies have been conducted in sub-Saharan Africa or in low human development countries. In studies done in all age groups, Shigella incidence varied from 0.6 to 107 episodes/1000 person-years. S. flexneri was the most commonly detected subgroup in the majority of studies. Case-fatality rates ranged from 0% to 2.6% in population-based studies and from 0% to 21% in facility-based studies. This review highlights the large gaps in data on the burden of Shigella infections for low human development index countries and, more specifically, for sub-Saharan Africa.

Full Text

Duke Authors

Cited Authors

  • Ram, PK; Crump, JA; Gupta, SK; Miller, MA; Mintz, ED

Published Date

  • May 2008

Published In

Volume / Issue

  • 136 / 5

Start / End Page

  • 577 - 603

PubMed ID

  • 17686195

Pubmed Central ID

  • PMC2870860

International Standard Serial Number (ISSN)

  • 0950-2688

Digital Object Identifier (DOI)

  • 10.1017/S0950268807009351


  • eng

Conference Location

  • England