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Retinopathy of prematurity in the United States.

Publication ,  Journal Article
Lad, EM; Nguyen, TC; Morton, JM; Moshfeghi, DM
Published in: Br J Ophthalmol
March 2008

AIMS: To determine the incidence of retinopathy of prematurity (ROP) based upon a national database and to identify baseline characteristics, demographic information, comorbidities, and surgical interventions. METHODS: The National Inpatient Sample, a representative sample of all US hospital discharges from 1997 to 2002, was queried for all newborn infants with and without ROP. Primary outcome variables included demographics, comorbidities, hospital length of stay (LOS), and hospital charges. Multivariate logistic regression was used to predict risk factors for ROP. RESULTS: 4.67 million live births were recorded during the study period. The total incidence of ROP was 0.12% overall and 7.35% for premature infants with LOS greater than 14 days. Newborns with ROP were more likely to be born at a teaching hospital and to have higher LOS and hospitalisation charges. The odds ratios for the development of ROP were greatest in infants weighing less than 1250 grams. The multivariate regression model revealed that only respiratory distress and intraventricular haemorrhage were predictive of the development of ROP and Hispanic infants were 33% more likely to develop ROP. CONCLUSION: This study represents the largest cohort of newborns analysed for ROP. The multivariate analysis emphasised the role of birth weight in extended-stay infants, as well as Hispanic race, respiratory distress syndrome, and intraventricular haemorrhage.

Duke Scholars

Published In

Br J Ophthalmol

DOI

EISSN

1468-2079

Publication Date

March 2008

Volume

92

Issue

3

Start / End Page

320 / 325

Location

England

Related Subject Headings

  • United States
  • Scleral Buckling
  • Retinopathy of Prematurity
  • Respiratory Distress Syndrome, Newborn
  • Ophthalmology & Optometry
  • Male
  • Length of Stay
  • Laser Coagulation
  • Infant, Very Low Birth Weight
  • Infant, Premature
 

Citation

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Chicago
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Lad, E. M., Nguyen, T. C., Morton, J. M., & Moshfeghi, D. M. (2008). Retinopathy of prematurity in the United States. Br J Ophthalmol, 92(3), 320–325. https://doi.org/10.1136/bjo.2007.126201
Lad, E. M., T. C. Nguyen, J. M. Morton, and D. M. Moshfeghi. “Retinopathy of prematurity in the United States.Br J Ophthalmol 92, no. 3 (March 2008): 320–25. https://doi.org/10.1136/bjo.2007.126201.
Lad EM, Nguyen TC, Morton JM, Moshfeghi DM. Retinopathy of prematurity in the United States. Br J Ophthalmol. 2008 Mar;92(3):320–5.
Lad, E. M., et al. “Retinopathy of prematurity in the United States.Br J Ophthalmol, vol. 92, no. 3, Mar. 2008, pp. 320–25. Pubmed, doi:10.1136/bjo.2007.126201.
Lad EM, Nguyen TC, Morton JM, Moshfeghi DM. Retinopathy of prematurity in the United States. Br J Ophthalmol. 2008 Mar;92(3):320–325.

Published In

Br J Ophthalmol

DOI

EISSN

1468-2079

Publication Date

March 2008

Volume

92

Issue

3

Start / End Page

320 / 325

Location

England

Related Subject Headings

  • United States
  • Scleral Buckling
  • Retinopathy of Prematurity
  • Respiratory Distress Syndrome, Newborn
  • Ophthalmology & Optometry
  • Male
  • Length of Stay
  • Laser Coagulation
  • Infant, Very Low Birth Weight
  • Infant, Premature