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Baseline risk factors for the development of primary open-angle glaucoma in the Ocular Hypertension Treatment Study.

Publication ,  Journal Article
Coleman, AL; Gordon, MO; Beiser, JA; Kass, MA; Ocular Hypertension Treatment Study,
Published in: Am J Ophthalmol
October 2004

PURPOSE: Higher baseline pattern standard deviation (PSD) and larger vertical cup-to-disk ratio (VC/D) were factors in the predictive model for the development of primary open-angle glaucoma (POAG) in the Ocular Hypertension Treatment Study. Because early changes in PSD and VC/D may be indicative of early POAG damage, we repeated the prediction model excluding PSD and VC/D. DESIGN: Reanalysis of baseline factors for the development of POAG. METHODS: We compared the hazard ratios for baseline factors predictive of POAG in the multivariate Cox proportional hazards model that included PSD and VC/D and in the model that excluded them. RESULTS: Hazard ratios for baseline factors predictive of POAG in Ocular Hypertension Treatment Study were not substantially affected by the inclusion or exclusion of PSD and VC/D in the proportional hazards model. CONCLUSION: Whether PSD or VC/D was included in the Cox proportional hazards model, the same baseline factors were statistically significant and their hazard ratios were essentially similar.

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Published In

Am J Ophthalmol

DOI

ISSN

0002-9394

Publication Date

October 2004

Volume

138

Issue

4

Start / End Page

684 / 685

Location

United States

Related Subject Headings

  • Risk Factors
  • Randomized Controlled Trials as Topic
  • Proportional Hazards Models
  • Ophthalmology & Optometry
  • Ocular Hypertension
  • Models, Biological
  • Intraocular Pressure
  • Humans
  • Glaucoma, Open-Angle
  • 3212 Ophthalmology and optometry
 

Citation

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MLA
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Coleman, A. L., Gordon, M. O., Beiser, J. A., Kass, M. A., & Ocular Hypertension Treatment Study, . (2004). Baseline risk factors for the development of primary open-angle glaucoma in the Ocular Hypertension Treatment Study. Am J Ophthalmol, 138(4), 684–685. https://doi.org/10.1016/j.ajo.2004.05.030
Coleman, Anne L., Mae O. Gordon, Julia A. Beiser, Michael A. Kass, and Michael A. Ocular Hypertension Treatment Study. “Baseline risk factors for the development of primary open-angle glaucoma in the Ocular Hypertension Treatment Study.Am J Ophthalmol 138, no. 4 (October 2004): 684–85. https://doi.org/10.1016/j.ajo.2004.05.030.
Coleman AL, Gordon MO, Beiser JA, Kass MA, Ocular Hypertension Treatment Study. Baseline risk factors for the development of primary open-angle glaucoma in the Ocular Hypertension Treatment Study. Am J Ophthalmol. 2004 Oct;138(4):684–5.
Coleman, Anne L., et al. “Baseline risk factors for the development of primary open-angle glaucoma in the Ocular Hypertension Treatment Study.Am J Ophthalmol, vol. 138, no. 4, Oct. 2004, pp. 684–85. Pubmed, doi:10.1016/j.ajo.2004.05.030.
Coleman AL, Gordon MO, Beiser JA, Kass MA, Ocular Hypertension Treatment Study. Baseline risk factors for the development of primary open-angle glaucoma in the Ocular Hypertension Treatment Study. Am J Ophthalmol. 2004 Oct;138(4):684–685.
Journal cover image

Published In

Am J Ophthalmol

DOI

ISSN

0002-9394

Publication Date

October 2004

Volume

138

Issue

4

Start / End Page

684 / 685

Location

United States

Related Subject Headings

  • Risk Factors
  • Randomized Controlled Trials as Topic
  • Proportional Hazards Models
  • Ophthalmology & Optometry
  • Ocular Hypertension
  • Models, Biological
  • Intraocular Pressure
  • Humans
  • Glaucoma, Open-Angle
  • 3212 Ophthalmology and optometry