Normal visual field test results following glaucomatous visual field end points in the Ocular Hypertension Treatment Study.

Published

Journal Article

OBJECTIVE: To compare the occurrence of normal visual field (VF) test results following 2 vs 3 consecutive, abnormal, reliable test results in the Ocular Hypertension Treatment Study. METHODS: The Ocular Hypertension Treatment Study is a prospective, multicenter follow-up study as part of a longitudinal randomized clinical trial. Sixty-four (68 eyes) of 1636 participants developed a VF primary open-angle glaucoma (POAG) end point. We compared the proportion of normal VF test results after a VF POAG end point among eyes whose VF abnormality was confirmed by 2 (n = 9 eyes) vs 3 (n = 59 eyes) consecutive, abnormal, reliable VF test results. RESULTS: The proportion of VF test results that were normal subsequent to a VF POAG end point in eyes whose abnormality was confirmed by 2 consecutive, abnormal, reliable test results was significantly higher (73 [66%] of 110) compared with eyes whose abnormality was confirmed by 3 consecutive, abnormal, reliable test results (46 [12%] of 381) (P = .01). CONCLUSIONS: A VF POAG end point confirmed by 3 consecutive, abnormal, reliable VF test results appears to have greater specificity and stability than either 1 or 2 consecutive, abnormal, reliable VF test results. However, some eyes whose VF POAG end point was confirmed by 3 consecutive, abnormal, reliable test results nonetheless had 1 or more normal test results on follow-up.

Full Text

Cited Authors

  • Keltner, JL; Johnson, CA; Levine, RA; Fan, J; Cello, KE; Kass, MA; Gordon, MO

Duke Contributors

Published Date

  • September 2005

Published In

Volume / Issue

  • 123 / 9

Start / End Page

  • 1201 - 1206

PubMed ID

  • 16157799

Pubmed Central ID

  • 16157799

International Standard Serial Number (ISSN)

  • 0003-9950

Digital Object Identifier (DOI)

  • 10.1001/archopht.123.9.1201

Language

  • eng

Conference Location

  • United States