Viral neoplastic transformation of hamster prostate tissue in vitro.

Journal Article (Journal Article)

Cultures of hamster prostatic tissues infected with simian virus 40 undergo transformation in vitro, and the transformed cells produce malignant tumors when injected into homologous hosts. Tartrate-inhibited acid phosphastase is found in the cultures of transformed cells and in the tumors they produce. Tartrate-inhibited acid phosphatase activity is elevated in the serum of tumor-bearing animals.

Full Text

Duke Authors

Cited Authors

  • Paulson, DF; Rabson, AS; Fraley, EE

Published Date

  • January 12, 1968

Published In

Volume / Issue

  • 159 / 3811

Start / End Page

  • 200 - 201

PubMed ID

  • 4294558

International Standard Serial Number (ISSN)

  • 0036-8075

Digital Object Identifier (DOI)

  • 10.1126/science.159.3811.200


  • eng

Conference Location

  • United States