Gray-scale inversion radiographic display for the detection of pulmonary nodules on chest radiographs.

Journal Article (Journal Article)

The purpose of this study was to investigate gray-scale inversion in nodule detection on chest radiography. Simulated nodules were superimposed randomly onto normal chest radiographs. Six radiologists interpreted 144 chest radiographs during three reading sessions: traditional presentation, inverted gray-scale, and a choice session allowing use of traditional and gray-scale inverted views. Sensitivity and specificity were used to assess accuracy based on presence or absence of a nodule. Gray-scale inversion and choice display sessions resulted in significantly higher nodule detection specificity and decreased sensitivity compared to traditional display. Gray-scale inversion may decrease false-positive nodule findings during chest X-ray interpretation.

Full Text

Duke Authors

Cited Authors

  • Lungren, MP; Samei, E; Barnhart, H; McAdams, HP; Leder, RA; Christensen, JD; Wylie, JD; Tan, JW; Li, X; Hurwitz, LM

Published Date

  • 2012

Published In

Volume / Issue

  • 36 / 5

Start / End Page

  • 515 - 521

PubMed ID

  • 22920355

Electronic International Standard Serial Number (EISSN)

  • 1873-4499

Digital Object Identifier (DOI)

  • 10.1016/j.clinimag.2012.01.009


  • eng

Conference Location

  • United States