Magnetoencephalographic recordings demonstrate attentional modulation of mismatch-related neural activity in human auditory cortex.
Journal Article (Clinical Trial;Journal Article)
It is widely agreed that the negative brain potential elicited at 150-200 ms by a deviant, less intense sound in a repetitive series can be modulated by attention. To investigate whether this modulation represents a genuine attention effect on the mismatch negativity (MMN) arising from auditory cortex or attention-related activity from another brain region, we recorded both the MMN and the mismatch magnetic field (MMF) elicited by such deviants in a dichotic listening task. Deviant tones in the attended ear elicited a sizable MMF that was well modeled as a dipolar source in auditory cortex. Both the MMN and MMF to unattended-ear deviants were highly attenuated. These findings support the view that the MMN/MMF elicited in auditory cortex by intensity deviants, and thus the underlying feature-analysis and mismatch-detection processes, are not strongly automatic but rather can be gated or suppressed if attention is strongly focused elsewhere.
Full Text
Duke Authors
Cited Authors
- Woldorff, MG; Hillyard, SA; Gallen, CC; Hampson, SR; Bloom, FE
Published Date
- May 1998
Published In
Volume / Issue
- 35 / 3
Start / End Page
- 283 - 292
PubMed ID
- 9564748
International Standard Serial Number (ISSN)
- 0048-5772
Digital Object Identifier (DOI)
- 10.1017/s0048577298961601
Language
- eng
Conference Location
- United States