Correlation of intralesional in vivo chemotherapy of line 10 hepatoma with in vitro drug sensitivity.

Journal Article (Journal Article)

The effects of intralesional chemotherapy with 7 different drugs on line 10 hepatoma grown in strain 2 guinea pigs were compared with the sensitivity of line 10 tumor cells in vitro, using a micro modification of the tumor stem assay with capillary tubes. A modified method was used to evaluate the in vitro dose-response curves. The correlation for in vivo/in vitro resistance was found to be 100% and for in vivo/in sensitivity it was 80%.

Full Text

Duke Authors

Cited Authors

  • Osman, FA; Bier, J; Bier, H; Siegel, T; Maurer, HR; Ohanian, S

Published Date

  • June 1, 1983

Published In

Volume / Issue

  • 1 / 2

Start / End Page

  • 118 - 127

PubMed ID

  • 6199438

International Standard Serial Number (ISSN)

  • 0737-1454

Digital Object Identifier (DOI)

  • 10.1002/stem.5530010206


  • eng

Conference Location

  • United States