Correlation of intralesional in vivo chemotherapy of line 10 hepatoma with in vitro drug sensitivity.
Journal Article (Journal Article)
The effects of intralesional chemotherapy with 7 different drugs on line 10 hepatoma grown in strain 2 guinea pigs were compared with the sensitivity of line 10 tumor cells in vitro, using a micro modification of the tumor stem assay with capillary tubes. A modified method was used to evaluate the in vitro dose-response curves. The correlation for in vivo/in vitro resistance was found to be 100% and for in vivo/in sensitivity it was 80%.
Full Text
Duke Authors
Cited Authors
- Osman, FA; Bier, J; Bier, H; Siegel, T; Maurer, HR; Ohanian, S
Published Date
- June 1, 1983
Published In
Volume / Issue
- 1 / 2
Start / End Page
- 118 - 127
PubMed ID
- 6199438
Pubmed Central ID
- 6199438
International Standard Serial Number (ISSN)
- 0737-1454
Digital Object Identifier (DOI)
- 10.1002/stem.5530010206
Language
- eng
Conference Location
- United States