Iron deficiency: lessons from anemic mice.

Journal Article (Journal Article)

Iron is an essential nutrient, and disorders of iron metabolism are common. Nonetheless, intestinal iron absorption and cellular iron transport are poorly understood. Biochemical approaches to elucidating these processes have yielded little in the past decade. As an alternative approach, we have begun to study spontaneous mouse mutants, that have inherited defects in key steps in iron transport. We have undertaken positional cloning of the gene responsible for microcytic anemia (gene symbol mk). This report describes the important characteristics of these mice, and our progress in studying them.

Full Text

Duke Authors

Cited Authors

  • Andrews, NC

Published Date

  • May 1997

Published In

Volume / Issue

  • 70 / 3

Start / End Page

  • 219 - 226

PubMed ID

  • 9544492

Pubmed Central ID

  • PMC2589100

International Standard Serial Number (ISSN)

  • 0044-0086


  • eng

Conference Location

  • United States