Iron deficiency: lessons from anemic mice.
Journal Article
Iron is an essential nutrient, and disorders of iron metabolism are common. Nonetheless, intestinal iron absorption and cellular iron transport are poorly understood. Biochemical approaches to elucidating these processes have yielded little in the past decade. As an alternative approach, we have begun to study spontaneous mouse mutants, that have inherited defects in key steps in iron transport. We have undertaken positional cloning of the gene responsible for microcytic anemia (gene symbol mk). This report describes the important characteristics of these mice, and our progress in studying them.
Full Text
Duke Authors
Cited Authors
- Andrews, NC
Published Date
- May 1997
Published In
Volume / Issue
- 70 / 3
Start / End Page
- 219 - 226
PubMed ID
- 9544492
Pubmed Central ID
- 9544492
International Standard Serial Number (ISSN)
- 0044-0086
Language
- eng
Conference Location
- United States