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Prothrombin measurement using a patient self-testing system

Publication ,  Journal Article
Andrews, M; Ansell, JL; Becker, DM; Becker, RC; Triplett, DA
Published in: American Journal of Clinical Pathology
2001

We enrolled 82 patients receiving oral anticoagulation in a pilot trial of a point-of-care (POC) prothrombin time (PT) device in a patient self-testing (PST) application in 7 US and Canadian hospital-based anticoagulation centers. The properly selected and suitably trained patients were given the PT device to test at home for 6 weeks. Patients returned within 3 hours of the self-test to the hospital clinic where a repeated test was performed by a health care professional using the patient's POC device (clinic). Blood specimens were obtained for routine laboratory PT determinations by the local hospital laboratory (hospital) and a reference laboratory. International Normalized Ratio agreement between the home test and the clinic test was excellent. Home results correlated well with reference laboratory results. Using the reference laboratory as a standard, 68% of hospital and 66% of home results matched the patient's therapeutic range classification of the reference laboratory result. Participants overwhelmingly reported satisfaction and willingness to perform the self-test. Our results confirm the equivalence of the PST PT and a reference laboratory result and suggest that PST PT technology is an appropriate and useful adjunct to routine oral anticoagulation monitoring methods.

Duke Scholars

Published In

American Journal of Clinical Pathology

Publication Date

2001

Volume

115

Issue

2

Start / End Page

280 / 287

Related Subject Headings

  • Pathology
  • 11 Medical and Health Sciences
 

Citation

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Chicago
ICMJE
MLA
NLM
Andrews, M., Ansell, J. L., Becker, D. M., Becker, R. C., & Triplett, D. A. (2001). Prothrombin measurement using a patient self-testing system. American Journal of Clinical Pathology, 115(2), 280–287.
Andrews, M., J. L. Ansell, D. M. Becker, R. C. Becker, and D. A. Triplett. “Prothrombin measurement using a patient self-testing system.” American Journal of Clinical Pathology 115, no. 2 (2001): 280–87.
Andrews M, Ansell JL, Becker DM, Becker RC, Triplett DA. Prothrombin measurement using a patient self-testing system. American Journal of Clinical Pathology. 2001;115(2):280–7.
Andrews, M., et al. “Prothrombin measurement using a patient self-testing system.” American Journal of Clinical Pathology, vol. 115, no. 2, 2001, pp. 280–87.
Andrews M, Ansell JL, Becker DM, Becker RC, Triplett DA. Prothrombin measurement using a patient self-testing system. American Journal of Clinical Pathology. 2001;115(2):280–287.

Published In

American Journal of Clinical Pathology

Publication Date

2001

Volume

115

Issue

2

Start / End Page

280 / 287

Related Subject Headings

  • Pathology
  • 11 Medical and Health Sciences