Reduction in oocyte number following prenatal exposure to a diet high in galactose.
Journal Article (Journal Article)
When pregnant rats were fed a 50 percent galactose diet there was a striking reduction in oocyte number in the offspring. The most prominent effects were noted after exposure to galactose during the premeiotic stages of oogenesis. Prenatal exposure to galactose or its metabolites may contribute to the premature ovarian failure characteristic of human galactosemia.
- Chen, YT; Mattison, DR; Feigenbaum, L; Fukui, H; Schulman, JD
- December 4, 1981
Volume / Issue
- 214 / 4525
Start / End Page
- 1145 - 1147
International Standard Serial Number (ISSN)
Digital Object Identifier (DOI)
- United States