Two-stage sampling in pharmaceutical applications.

Published

Journal Article

In the pharmaceutical industry, some tests for quality assurance before, during and after the manufacture of a drug product involve a two-stage sampling technique. We propose statistical testing procedures in a two-stage sampling problem with large within-class sample sizes. We also derive a two-stage sampling plan by minimizing the expected squared volume (or the generalized variance) of the confidence region related to the test. We present two examples to illustrate the proposed methods.

Full Text

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Duke Authors

Chow, Shein-Chung

Cited Authors

Shao, J; Chow, SC

Published Date

November 15, 1993

Published In

Statistics in Medicine

Volume / Issue

12 / 21

Start / End Page

1999 - 2008

PubMed ID

8296110

Pubmed Central ID

8296110

International Standard Serial Number (ISSN)

0277-6715

Language

Conference Location

England