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Colony-stimulating factors: clinical applications.

Publication ,  Journal Article
Blackwell, S; Crawford, J
Published in: Pharmacotherapy
1992

Recombinant human colony-stimulating factors (CSFs) have potential for wide use in the areas of oncology and infectious disease. Granulocyte CSF and granulocyte-macrophage CSF currently are approved for use in the treatment of neutropenia associated with standard-dose cancer chemotherapy and bone marrow transplantation, respectively. Other settings in which these agents have shown promise are dose-intensive chemotherapy, enhancement of progenitor cell support, primary and acquired neutropenias, myelodysplasia, aplastic anemia, and cytopenias associated with human immunodeficiency virus infection or myelosuppressive therapies for such infection or related conditions. Clinical findings in these areas are encouraging, and potential exists for additional applications of the CSFs.

Duke Scholars

Published In

Pharmacotherapy

ISSN

0277-0008

Publication Date

1992

Volume

12

Issue

2 Pt 2

Start / End Page

20S / 31S

Location

United States

Related Subject Headings

  • Transplantation, Autologous
  • Pharmacology & Pharmacy
  • Pancytopenia
  • Neutropenia
  • Neoplasms
  • Myelodysplastic Syndromes
  • Immunologic Factors
  • Humans
  • Hematopoiesis
  • HIV Infections
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Blackwell, S., & Crawford, J. (1992). Colony-stimulating factors: clinical applications. Pharmacotherapy, 12(2 Pt 2), 20S-31S.
Blackwell, S., and J. Crawford. “Colony-stimulating factors: clinical applications.Pharmacotherapy 12, no. 2 Pt 2 (1992): 20S-31S.
Blackwell S, Crawford J. Colony-stimulating factors: clinical applications. Pharmacotherapy. 1992;12(2 Pt 2):20S-31S.
Blackwell, S., and J. Crawford. “Colony-stimulating factors: clinical applications.Pharmacotherapy, vol. 12, no. 2 Pt 2, 1992, pp. 20S-31S.
Blackwell S, Crawford J. Colony-stimulating factors: clinical applications. Pharmacotherapy. 1992;12(2 Pt 2):20S-31S.

Published In

Pharmacotherapy

ISSN

0277-0008

Publication Date

1992

Volume

12

Issue

2 Pt 2

Start / End Page

20S / 31S

Location

United States

Related Subject Headings

  • Transplantation, Autologous
  • Pharmacology & Pharmacy
  • Pancytopenia
  • Neutropenia
  • Neoplasms
  • Myelodysplastic Syndromes
  • Immunologic Factors
  • Humans
  • Hematopoiesis
  • HIV Infections