Prognosis of patients with cirrhosis and chronic liver disease admitted to the medical intensive care unit.


Journal Article

Patients with hepatic failure admitted to the medical ICU (MICU) generally have a poor prognosis. To determine if there were readily identifiable clinical factors associated with a high predictive value for outcome, we reviewed retrospectively the charts of 100 patients with serious liver disease admitted to the MICU. The overall mortality of the group was 64%. We found that Child's class, a need for mechanical ventilation, and an elevated serum creatinine had the greatest prognostic significance. Ninety-one percent of the patients receiving assisted ventilation, 89% of the patients in Child's class C, and 93% of the patients with creatinine values greater than 1.3 mg/dl died during their MICU admission. Furthermore, a multivariant regression analysis indicated that patients in Child's class C receiving mechanical ventilation who had an abnormal serum creatinine (greater than 1.3 mg/dl) during the first 72 h in the MICU had only a 2% survival rate.

Full Text

Duke Authors

Cited Authors

  • Shellman, RG; Fulkerson, WJ; DeLong, E; Piantadosi, CA

Published Date

  • July 1988

Published In

Volume / Issue

  • 16 / 7

Start / End Page

  • 671 - 678

PubMed ID

  • 3371043

Pubmed Central ID

  • 3371043

International Standard Serial Number (ISSN)

  • 0090-3493

Digital Object Identifier (DOI)

  • 10.1097/00003246-198807000-00005


  • eng

Conference Location

  • United States