Prognosis of patients with cirrhosis and chronic liver disease admitted to the medical intensive care unit.

Journal Article (Journal Article)

Patients with hepatic failure admitted to the medical ICU (MICU) generally have a poor prognosis. To determine if there were readily identifiable clinical factors associated with a high predictive value for outcome, we reviewed retrospectively the charts of 100 patients with serious liver disease admitted to the MICU. The overall mortality of the group was 64%. We found that Child's class, a need for mechanical ventilation, and an elevated serum creatinine had the greatest prognostic significance. Ninety-one percent of the patients receiving assisted ventilation, 89% of the patients in Child's class C, and 93% of the patients with creatinine values greater than 1.3 mg/dl died during their MICU admission. Furthermore, a multivariant regression analysis indicated that patients in Child's class C receiving mechanical ventilation who had an abnormal serum creatinine (greater than 1.3 mg/dl) during the first 72 h in the MICU had only a 2% survival rate.

Full Text

Duke Authors

Cited Authors

  • Shellman, RG; Fulkerson, WJ; DeLong, E; Piantadosi, CA

Published Date

  • July 1988

Published In

Volume / Issue

  • 16 / 7

Start / End Page

  • 671 - 678

PubMed ID

  • 3371043

International Standard Serial Number (ISSN)

  • 0090-3493

Digital Object Identifier (DOI)

  • 10.1097/00003246-198807000-00005


  • eng

Conference Location

  • United States