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Subcortical hyperintensities on brain magnetic resonance imaging: a comparison of normal and bipolar subjects.

Publication ,  Journal Article
Figiel, GS; Krishnan, KR; Rao, VP; Doraiswamy, M; Ellinwood, EH; Nemeroff, CB; Evans, D; Boyko, O
Published in: J Neuropsychiatry Clin Neurosci
1991

Bipolar disorder has been reported to occur frequently in a number of subcortical diseases. This suggests that subcortical structures may be involved in the etiology of bipolar disorder in some patients. With the advent of brain magnetic resonance imaging (MRI), in vivo visualization of the subcortical white and gray matter is now possible, allowing the examination of these structures. The authors report a higher occurrence of deep white matter lesions in bipolar patients (44%) compared with age-matched controls (6%). The neuroanatomic and clinical correlates of these lesions will be discussed, along with their potential pathophysiologic significance.

Duke Scholars

Published In

J Neuropsychiatry Clin Neurosci

DOI

ISSN

0895-0172

Publication Date

1991

Volume

3

Issue

1

Start / End Page

18 / 22

Location

United States

Related Subject Headings

  • Psychiatry
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Female
  • Brain
  • Bipolar Disorder
  • Adult
  • 3202 Clinical sciences
 

Citation

APA
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ICMJE
MLA
NLM
Figiel, G. S., Krishnan, K. R., Rao, V. P., Doraiswamy, M., Ellinwood, E. H., Nemeroff, C. B., … Boyko, O. (1991). Subcortical hyperintensities on brain magnetic resonance imaging: a comparison of normal and bipolar subjects. J Neuropsychiatry Clin Neurosci, 3(1), 18–22. https://doi.org/10.1176/jnp.3.1.18
Figiel, G. S., K. R. Krishnan, V. P. Rao, M. Doraiswamy, E. H. Ellinwood, C. B. Nemeroff, D. Evans, and O. Boyko. “Subcortical hyperintensities on brain magnetic resonance imaging: a comparison of normal and bipolar subjects.J Neuropsychiatry Clin Neurosci 3, no. 1 (1991): 18–22. https://doi.org/10.1176/jnp.3.1.18.
Figiel GS, Krishnan KR, Rao VP, Doraiswamy M, Ellinwood EH, Nemeroff CB, et al. Subcortical hyperintensities on brain magnetic resonance imaging: a comparison of normal and bipolar subjects. J Neuropsychiatry Clin Neurosci. 1991;3(1):18–22.
Figiel, G. S., et al. “Subcortical hyperintensities on brain magnetic resonance imaging: a comparison of normal and bipolar subjects.J Neuropsychiatry Clin Neurosci, vol. 3, no. 1, 1991, pp. 18–22. Pubmed, doi:10.1176/jnp.3.1.18.
Figiel GS, Krishnan KR, Rao VP, Doraiswamy M, Ellinwood EH, Nemeroff CB, Evans D, Boyko O. Subcortical hyperintensities on brain magnetic resonance imaging: a comparison of normal and bipolar subjects. J Neuropsychiatry Clin Neurosci. 1991;3(1):18–22.
Journal cover image

Published In

J Neuropsychiatry Clin Neurosci

DOI

ISSN

0895-0172

Publication Date

1991

Volume

3

Issue

1

Start / End Page

18 / 22

Location

United States

Related Subject Headings

  • Psychiatry
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Female
  • Brain
  • Bipolar Disorder
  • Adult
  • 3202 Clinical sciences