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Intraoperative assessment of left ventricular heterogeneity.

Publication ,  Journal Article
Douglas, PS; Reichek, N; Franklin, K; Muhammad, A; Sutton, MG; Harken, A
Published in: Am Heart J
August 1986

To evaluate regional differences in thickness and systolic function of human myocardium perfused by angiographically normal coronary arteries in valvular and ischemic heart disease, we performed intraoperative epicardial M-mode mapping of ventriculographically normal wall regions (perfused by normal coronary arteries) in 22 subjects undergoing either coronary bypass surgery for stenoses in other vessels (n = 15) or mitral (n = 5) and/or aortic valve replacement (n = 4). In patients in whom both anterior and inferior walls were ventriculographically normal and normally perfused (n = 6), comparison of the two walls showed the anterior wall to be thicker at both end diastole and end systole, but there was no difference in the percentage of systolic thickening. Analysis of myocardium along the long axis revealed apical sites to be thinner than basal sites at both end diastole and end systole. Percentage of systolic thickening was also increased at apical sites. In patients in whom only the anterior wall was normal, a similar decrease in anterior wall thickness was noted at the apex. Thus systematic regional heterogeneity along both the left ventricular major and minor axes is found in the chronically diseased human heart as it is in the normal heart. Assessment of myocardial structure and function and of the effects of therapeutic interventions must take this heterogeneity into account.

Duke Scholars

Published In

Am Heart J

DOI

ISSN

0002-8703

Publication Date

August 1986

Volume

112

Issue

2

Start / End Page

344 / 349

Location

United States

Related Subject Headings

  • Myocardial Contraction
  • Intraoperative Care
  • Humans
  • Heart Ventricles
  • Heart Valve Prosthesis
  • Heart Diseases
  • Echocardiography
  • Coronary Artery Bypass
  • Cardiovascular System & Hematology
  • 3201 Cardiovascular medicine and haematology
 

Citation

APA
Chicago
ICMJE
MLA
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Douglas, P. S., Reichek, N., Franklin, K., Muhammad, A., Sutton, M. G., & Harken, A. (1986). Intraoperative assessment of left ventricular heterogeneity. Am Heart J, 112(2), 344–349. https://doi.org/10.1016/0002-8703(86)90273-5
Douglas, P. S., N. Reichek, K. Franklin, A. Muhammad, M. G. Sutton, and A. Harken. “Intraoperative assessment of left ventricular heterogeneity.Am Heart J 112, no. 2 (August 1986): 344–49. https://doi.org/10.1016/0002-8703(86)90273-5.
Douglas PS, Reichek N, Franklin K, Muhammad A, Sutton MG, Harken A. Intraoperative assessment of left ventricular heterogeneity. Am Heart J. 1986 Aug;112(2):344–9.
Douglas, P. S., et al. “Intraoperative assessment of left ventricular heterogeneity.Am Heart J, vol. 112, no. 2, Aug. 1986, pp. 344–49. Pubmed, doi:10.1016/0002-8703(86)90273-5.
Douglas PS, Reichek N, Franklin K, Muhammad A, Sutton MG, Harken A. Intraoperative assessment of left ventricular heterogeneity. Am Heart J. 1986 Aug;112(2):344–349.
Journal cover image

Published In

Am Heart J

DOI

ISSN

0002-8703

Publication Date

August 1986

Volume

112

Issue

2

Start / End Page

344 / 349

Location

United States

Related Subject Headings

  • Myocardial Contraction
  • Intraoperative Care
  • Humans
  • Heart Ventricles
  • Heart Valve Prosthesis
  • Heart Diseases
  • Echocardiography
  • Coronary Artery Bypass
  • Cardiovascular System & Hematology
  • 3201 Cardiovascular medicine and haematology