Genomics and hypertension: concepts, potentials, and opportunities.

Journal Article (Journal Article;Review)

We are at the beginning of a biological revolution, spurred on by the Human Genome Project and associated studies. Within the next few years, expressed sequence tags (ESTs) representing all sequences expressed in humans will be determined and their genomic positions will be defined (STSs). The discovery of all the variants in the human genome that contribute to the genetic diversity of the human population will result in the construction of dense polymorphic maps. The rapid growth of the EST, STS, and single-nucleotide polymorphism (SNP) databases, coupled with impressive technological advances, will surely have a dramatic effect on biomedical research. In this review, we will examine the recent advances in genetics and genomics and place these within the context of medical research and patient care, with an emphasis on studies in the cardiovascular system.

Full Text

Duke Authors

Cited Authors

  • Pratt, RE; Dzau, VJ

Published Date

  • January 1999

Published In

Volume / Issue

  • 33 / 1 Pt 2

Start / End Page

  • 238 - 247

PubMed ID

  • 9931111

International Standard Serial Number (ISSN)

  • 0194-911X

Digital Object Identifier (DOI)

  • 10.1161/01.hyp.33.1.238


  • eng

Conference Location

  • United States