Partial purification of a prorenin activating enzyme in the aortic wall.

Journal Article

The presence of a prorenin activating enzyme in the blood vessel wall may have important physiological implications. The putative enzyme may be involved with the endogenous production of active renin (a key enzyme in the vascular renin angiotensin system) or with the activation of circulating prorenin which had been taken up into the vessel wall. This study demonstrates the existence of a putative prorenin activating enzyme in the bovine aorta. Partial purification and characterization of the enzyme are described.

Full Text

Duke Authors

Cited Authors

  • Tang, SS; Dzau, VJ

Published Date

  • 1988

Published In

Volume / Issue

  • 10 / 6

Start / End Page

  • 1251 - 1257

PubMed ID

  • 3066530

Pubmed Central ID

  • 3066530

International Standard Serial Number (ISSN)

  • 0730-0077

Digital Object Identifier (DOI)

  • 10.1080/07300077.1988.11878915

Language

  • eng

Conference Location

  • United States