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Dissimilar courses of twins with leukemia.

Publication ,  Journal Article
Stewart, SJ; Shepherd, DA; Steuber, CP; Starling, KA; Falletta, JM
Published in: Med Pediatr Oncol
1977

Twin girls, genetically identical, probably experienced different leukemogenic events and presented with acute lymphocytic leukemia 6 years apart. Their clinical presentations were similar, but they received significantly different therapy. The first twin died 34 months after diagnosis following multiple remissions and relapses, having received single-drug maintenance. The second twin remains free of apparent disease 60 months after diagnosis, following vincristine and prednisone induction, 6-mercaptopurine maintenance, methotrexate and prednisone reinforcement, and central nervous system treatment of occult disease. Their dissimilar clinical courses may have been due to different leukemogenic events and/or markedly different therapeutic programs.

Duke Scholars

Published In

Med Pediatr Oncol

DOI

ISSN

0098-1532

Publication Date

1977

Volume

3

Issue

3

Start / End Page

231 / 235

Location

United States

Related Subject Headings

  • Vincristine
  • Remission, Spontaneous
  • Recurrence
  • Prednisone
  • Oncology & Carcinogenesis
  • Methotrexate
  • Mercaptopurine
  • Leukemia, Lymphoid
  • Hydrocortisone
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
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Stewart, S. J., Shepherd, D. A., Steuber, C. P., Starling, K. A., & Falletta, J. M. (1977). Dissimilar courses of twins with leukemia. Med Pediatr Oncol, 3(3), 231–235. https://doi.org/10.1002/mpo.2950030303
Stewart, S. J., D. A. Shepherd, C. P. Steuber, K. A. Starling, and J. M. Falletta. “Dissimilar courses of twins with leukemia.Med Pediatr Oncol 3, no. 3 (1977): 231–35. https://doi.org/10.1002/mpo.2950030303.
Stewart SJ, Shepherd DA, Steuber CP, Starling KA, Falletta JM. Dissimilar courses of twins with leukemia. Med Pediatr Oncol. 1977;3(3):231–5.
Stewart, S. J., et al. “Dissimilar courses of twins with leukemia.Med Pediatr Oncol, vol. 3, no. 3, 1977, pp. 231–35. Pubmed, doi:10.1002/mpo.2950030303.
Stewart SJ, Shepherd DA, Steuber CP, Starling KA, Falletta JM. Dissimilar courses of twins with leukemia. Med Pediatr Oncol. 1977;3(3):231–235.

Published In

Med Pediatr Oncol

DOI

ISSN

0098-1532

Publication Date

1977

Volume

3

Issue

3

Start / End Page

231 / 235

Location

United States

Related Subject Headings

  • Vincristine
  • Remission, Spontaneous
  • Recurrence
  • Prednisone
  • Oncology & Carcinogenesis
  • Methotrexate
  • Mercaptopurine
  • Leukemia, Lymphoid
  • Hydrocortisone
  • Humans