The MDCT has advantages that are uniquely suited to imaging of infants and children. This is one reason why the use of CT has continued to increase. There is also, however, an increased complexity with this technology. Because diagnosis is dependent on adequate quality, and inappropriately high radiation doses can result from poor technique, it is necessary for the radiologist to be familiar with the techniques of MDCT in children. With attention to these techniques, and appropriate application of MDCT, it is possible to maximize the yield while minimizing the risk to children.