Genetic sampling error of distance (delta(mu))2 and variation in mutation rate among microsatellite loci.

Published

Journal Article

An expression is obtained for the time-dependent variance of the microsatellite genetic distance (delta(mu))2 when the mutation rate is allowed to vary randomly among loci. An estimator is presented for the coefficient of variation, C(w), in the mutation rate. Estimated values of C(w) from genetic distances between African and non-African populations were less than 100%. Caveats to this conclusion are discussed.

Full Text

Cited Authors

  • Zhivotovsky, LA; Goldstein, DB; Feldman, MW

Published Date

  • December 2001

Published In

Volume / Issue

  • 18 / 12

Start / End Page

  • 2141 - 2145

PubMed ID

  • 11719562

Pubmed Central ID

  • 11719562

Electronic International Standard Serial Number (EISSN)

  • 1537-1719

International Standard Serial Number (ISSN)

  • 0737-4038

Digital Object Identifier (DOI)

  • 10.1093/oxfordjournals.molbev.a003759

Language

  • eng