Nonclinality of molecular variation implicates selection in maintaining a morphological cline of Drosophila melanogaster.


Journal Article

One general approach for assessing whether phenotypic variation is due to selection is to test its correlation with presumably neutral molecular variation. Neutral variation is determined by population history, the most likely alternative explanation of spatial genetic structure, whereas phenotypic variation may be influenced by the spatial pattern of selection pressure. Several methods for comparing the spatial apportionment of molecular and morphological variation have been used. Here, we present an analysis of variance framework that compares the magnitudes of latitudinal effects for molecular and morphological variation along a body size cline in Australian Drosophila populations. Explicit incorporation of the relevant environmental gradient can result in a simple and powerful test of selection. For the Australian cline, our analysis provides strong internal evidence that the cline is due to selection.

Full Text

Cited Authors

  • Gockel, J; Kennington, WJ; Hoffmann, A; Goldstein, DB; Partridge, L

Published Date

  • May 2001

Published In

Volume / Issue

  • 158 / 1

Start / End Page

  • 319 - 323

PubMed ID

  • 11333239

Pubmed Central ID

  • 11333239

Electronic International Standard Serial Number (EISSN)

  • 1943-2631

International Standard Serial Number (ISSN)

  • 0016-6731


  • eng