Characterization of health-related quality of life in heart failure patients with preserved versus low ejection fraction in CHARM.

Published

Journal Article

BACKGROUND: Limited comparative studies assessing the health-related quality of life (HRQL) in heart failure (HF) patients with preserved vs. low ejection fraction (LVEF) have been disparate. AIMS: The aims of this study were a) to characterize HRQL in a large population of HF patients with preserved and low LVEF and b) to determine the factors associated with worse HRQL. METHODS: Patients with symptomatic HF (NYHA Class II-IV) enrolled in the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) HRQL study completed the Minnesota Living with Heart Failure questionnaire at randomization. Patients were stratified into 2 HF cohorts: preserved LVEF (>40%) and low LVEF (

Full Text

Duke Authors

Cited Authors

  • Lewis, EF; Lamas, GA; O'Meara, E; Granger, CB; Dunlap, ME; McKelvie, RS; Probstfield, JL; Young, JB; Michelson, EL; Halling, K; Carlsson, J; Olofsson, B; McMurray, JJV; Yusuf, S; Swedberg, K; Pfeffer, MA; CHARM Investigators,

Published Date

  • January 1, 2007

Published In

Volume / Issue

  • 9 / 1

Start / End Page

  • 83 - 91

PubMed ID

  • 17188020

Pubmed Central ID

  • 17188020

Electronic International Standard Serial Number (EISSN)

  • 1879-0844

International Standard Serial Number (ISSN)

  • 1388-9842

Digital Object Identifier (DOI)

  • 10.1016/j.ejheart.2006.10.012

Language

  • eng