Phylogenetic distribution of Antennapedia-like homoeo boxes

Journal Article (Journal Article)

The homoeo box is a conserved protein-coding DNA sequence present in several genes in arthropods, annelids and vertebrates1-4. Two distinct classes of homoeo box have been identified-the Antennapedia (Antp) class1,5 and the engrailed class6-8. In insects, both classes are found in genes involved in regulating development. We have therefore investigated the phylogenetic distribution of Antp-like homoeo boxes to explore the possibility of a link between their presence and developmental strategy1,9-11. The distribution data also give important insight into the origin of homoeo boxes and the phytogeny of the animal kingdom. © 1986 Nature Publishing Group.

Full Text

Duke Authors

Cited Authors

  • Holland, PWH; Hogan, BLM

Published Date

  • December 1, 1986

Published In

Volume / Issue

  • 321 / 6067

Start / End Page

  • 251 - 253

International Standard Serial Number (ISSN)

  • 0028-0836

Digital Object Identifier (DOI)

  • 10.1038/321251a0

Citation Source

  • Scopus