Quantitative laser scanning confocal autofluorescence microscopy of normal and premalignant colonic tissues


Journal Article

Laser-induced fluorescence (LIF) spectroscopy of tissues is proposed as an adjunct to endoscopy for gastrointestinal diagnosis because of its potential for early detection of premalignant lesions in situ. Spatially localized quantitative analysis of the fluorescence yield from tissue specimens was performed by careful calibration of the microscope sensitivity as a function of detector gain, confocal aperture size, image scan speed, and microscope spectral throughput.

Duke Authors

Cited Authors

  • Wang, HW; Willis, J; Sivak, MV; Izatt, JA

Published Date

  • January 1, 1997

Published In

Volume / Issue

  • 11 /

Start / End Page

  • 71 - 72

International Standard Serial Number (ISSN)

  • 1092-8081

Citation Source

  • Scopus