Optical coherence tomography of the human retina.


Journal Article

OBJECTIVE: To demonstrate optical coherence tomography for high-resolution, noninvasive imaging of the human retina. Optical coherence tomography is a new imaging technique analogous to ultrasound B scan that can provide cross-sectional images of the retina with micrometer-scale resolution. DESIGN: Survey optical coherence tomographic examination of the retina, including the macula and optic nerve head in normal human subjects. SETTING: Research laboratory. PARTICIPANTS: Convenience sample of normal human subjects. MAIN OUTCOME MEASURES: Correlation of optical coherence retinal tomographs with known normal retinal anatomy. RESULTS: Optical coherence tomographs can discriminate the cross-sectional morphologic features of the fovea and optic disc, the layered structure of the retina, and normal anatomic variations in retinal and retinal nerve fiber layer thicknesses with 10-microns depth resolution. CONCLUSION: Optical coherence tomography is a potentially useful technique for high depth resolution, cross-sectional examination of the fundus.

Full Text

Duke Authors

Cited Authors

  • Hee, MR; Izatt, JA; Swanson, EA; Huang, D; Schuman, JS; Lin, CP; Puliafito, CA; Fujimoto, JG

Published Date

  • March 1995

Published In

Volume / Issue

  • 113 / 3

Start / End Page

  • 325 - 332

PubMed ID

  • 7887846

Pubmed Central ID

  • 7887846

Electronic International Standard Serial Number (EISSN)

  • 1538-3601

International Standard Serial Number (ISSN)

  • 0003-9950

Digital Object Identifier (DOI)

  • 10.1001/archopht.1995.01100030081025


  • eng