The identification of experimentally induced appendicitis using in vitro nuclear magnetic resonance

Journal Article

Appendicitis was induced in six New Zealand white rabbits. The appendices from these animals had significantly higher spin-lattice relaxation times, T1, as determined in vitro by nuclear magnetic resonance (NMR) (10 controls vs 6 experimentals, 413 ± 23 vs 455 ± 41, X ± SD, P < (0.02). T1 correlated significantly with the water content of the appendiceal tissue (P < 0.001). These findings suggest that in vivo NMR imaging techniques weighted on T1 might be able to identify human appendicitis noninvasively by detecting localized edema. © 1985.

Cited Authors

  • Jacobs, DO; Clarke, JR; Settle, RG; Sachdeva, AK; Wheeler, JE; Trerotola, SO; Wolf, GL; Rombeau, JL

Published Date

  • 1985

Published In

Volume / Issue

  • 39 / 1

Start / End Page

  • 16 - 24

International Standard Serial Number (ISSN)

  • 0022-4804