H and 3
He magnetic resonance microscopy of the lung
Using in vivo magnetic resonance microscopy, registered 1H and hyperpolarized 3He images of the rat lung were obtained with a resolution of 0.098 × 0.098 × 0.469 mm (4.5 × 10-3 mm3). The requisite stability and SNR was achieved through an integration of scan-synchronous ventilation, dual-frequency RF coils, anisotropic projection encoding, and variable RF excitation. The total acquisition time was 21 min for the 3He images and 64 min for the 1H image. Airways down to the 6th and 7th orders are clearly visible. © 2001 Wiley-Liss, Inc.
Johnson, GA; Cofer, GP; Hedlund, LW; Maronpot, RR; Suddarth, SA
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