Conservation of the 3' terminal nucleotide sequences of Ebola and Marburg virus.


Journal Article

The 3' RNA base sequences of several Marburg (MBG) and Ebola (EBO) virus isolates have been determined. A comparison of these 3' terminal noncoding sequences with those of other negative strand RNA viruses suggests a unique phylogenic niche for Marburg and Ebola viruses. The translation initiation site and 35 N-terminal amino acids of the 3' proximal coding gene of a Zaire strain of Ebola virus was predicted. In addition, putative leader RNA sequences preceding the first gene are discussed in terms of possible regulatory functions.

Full Text

Duke Authors

Cited Authors

  • Kiley, MP; Wilusz, J; McCormick, JB; Keene, JD

Published Date

  • March 1, 1986

Published In

Volume / Issue

  • 149 / 2

Start / End Page

  • 251 - 254

PubMed ID

  • 3946083

Pubmed Central ID

  • 3946083

International Standard Serial Number (ISSN)

  • 0042-6822

Digital Object Identifier (DOI)

  • 10.1016/0042-6822(86)90127-3


  • eng

Conference Location

  • United States