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Echocardiographic documentation of vegetative lesions in infective endocarditis: clinical implications.

Publication ,  Journal Article
Stewart, JA; Silimperi, D; Harris, P; Wise, NK; Fraker, TD; Kisslo, JA
Published in: Circulation
February 1980

Eighty-seven patients with the clinical syndrome of infective endocarditis were examined by M-mode and two-dimensional echocardiography. Patients were divided into two groups based on the presence or absence of echocardiographically detected vegetative lesions. Group 1 consisted of 47 patients with one or more vegetations. Group 2 consisted of 40 patients without evidence of vegetations. Group 1 patients had a higher rate of complications: emboli, congestive heart failure and the need for surgical intervention. Analysis of morphologic characteristics of the vegetations in group 1 was of no predictive value for complications in individual patients. Two-thirds of the vegetations persisted unaltered well beyond the period of bacteriologic cure without significant complications. No characteristic alteration of the vegetations predicted the efficacy of medical therapy. Although the detection of vegetations by echocardiography in patients with the clinical syndrome of endocarditis clearly identifies a subgroup at risk for complications, decisions regarding clinical management made solely on the basis of the presence or absence of vegetative lesions are hazardous. Management of such patients must continue to be based on the clinical integration of multiple factors.

Duke Scholars

Published In

Circulation

DOI

ISSN

0009-7322

Publication Date

February 1980

Volume

61

Issue

2

Start / End Page

374 / 380

Location

United States

Related Subject Headings

  • Streptococcus
  • Staphylococcus aureus
  • Mortality
  • Middle Aged
  • Humans
  • Heart Failure
  • Follow-Up Studies
  • Endocarditis, Bacterial
  • Embolism
  • Echocardiography
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Stewart, J. A., Silimperi, D., Harris, P., Wise, N. K., Fraker, T. D., & Kisslo, J. A. (1980). Echocardiographic documentation of vegetative lesions in infective endocarditis: clinical implications. Circulation, 61(2), 374–380. https://doi.org/10.1161/01.cir.61.2.374
Stewart, J. A., D. Silimperi, P. Harris, N. K. Wise, T. D. Fraker, and J. A. Kisslo. “Echocardiographic documentation of vegetative lesions in infective endocarditis: clinical implications.Circulation 61, no. 2 (February 1980): 374–80. https://doi.org/10.1161/01.cir.61.2.374.
Stewart JA, Silimperi D, Harris P, Wise NK, Fraker TD, Kisslo JA. Echocardiographic documentation of vegetative lesions in infective endocarditis: clinical implications. Circulation. 1980 Feb;61(2):374–80.
Stewart, J. A., et al. “Echocardiographic documentation of vegetative lesions in infective endocarditis: clinical implications.Circulation, vol. 61, no. 2, Feb. 1980, pp. 374–80. Pubmed, doi:10.1161/01.cir.61.2.374.
Stewart JA, Silimperi D, Harris P, Wise NK, Fraker TD, Kisslo JA. Echocardiographic documentation of vegetative lesions in infective endocarditis: clinical implications. Circulation. 1980 Feb;61(2):374–380.

Published In

Circulation

DOI

ISSN

0009-7322

Publication Date

February 1980

Volume

61

Issue

2

Start / End Page

374 / 380

Location

United States

Related Subject Headings

  • Streptococcus
  • Staphylococcus aureus
  • Mortality
  • Middle Aged
  • Humans
  • Heart Failure
  • Follow-Up Studies
  • Endocarditis, Bacterial
  • Embolism
  • Echocardiography