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Viloxazine in the treatment of depressive neurosis: A placebo and standard (imipramine) controlled clinical study

Publication ,  Journal Article
Petrie, WM; McEvoy, JP; Wilson, WH; Ban, TA; Guy, W
Published in: International Pharmacopsychiatry
1980

In a 4-week double-blind trial, 33 patients with depressive neurosis were randomly assigned to either viloxazine, imipramine or placebo. Statistically significant improvement was observed in all treatment groups. Imipramine exhibited significant improvement earlier in depressive symptoms, while viloxazine showed significant improvement earlier in anxious symptoms. The same frequency of treatment emergent symptoms occurred in the treatment groups. Premature termination as a consequence of adverse reactions was required in only 1 viloxazine and 1 placebo patient.

Duke Scholars

Published In

International Pharmacopsychiatry

ISSN

0020-8272

Publication Date

1980

Volume

15

Issue

3

Start / End Page

193 / 196

Related Subject Headings

  • Psychiatry
  • 1702 Cognitive Sciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences
 

Citation

APA
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ICMJE
MLA
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Petrie, W. M., McEvoy, J. P., Wilson, W. H., Ban, T. A., & Guy, W. (1980). Viloxazine in the treatment of depressive neurosis: A placebo and standard (imipramine) controlled clinical study. International Pharmacopsychiatry, 15(3), 193–196.
Petrie, W. M., J. P. McEvoy, W. H. Wilson, T. A. Ban, and W. Guy. “Viloxazine in the treatment of depressive neurosis: A placebo and standard (imipramine) controlled clinical study.” International Pharmacopsychiatry 15, no. 3 (1980): 193–96.
Petrie WM, McEvoy JP, Wilson WH, Ban TA, Guy W. Viloxazine in the treatment of depressive neurosis: A placebo and standard (imipramine) controlled clinical study. International Pharmacopsychiatry. 1980;15(3):193–6.
Petrie, W. M., et al. “Viloxazine in the treatment of depressive neurosis: A placebo and standard (imipramine) controlled clinical study.” International Pharmacopsychiatry, vol. 15, no. 3, 1980, pp. 193–96.
Petrie WM, McEvoy JP, Wilson WH, Ban TA, Guy W. Viloxazine in the treatment of depressive neurosis: A placebo and standard (imipramine) controlled clinical study. International Pharmacopsychiatry. 1980;15(3):193–196.

Published In

International Pharmacopsychiatry

ISSN

0020-8272

Publication Date

1980

Volume

15

Issue

3

Start / End Page

193 / 196

Related Subject Headings

  • Psychiatry
  • 1702 Cognitive Sciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences