Viloxazine in the treatment of depressive neurosis: A placebo and standard (imipramine) controlled clinical study

Journal Article

In a 4-week double-blind trial, 33 patients with depressive neurosis were randomly assigned to either viloxazine, imipramine or placebo. Statistically significant improvement was observed in all treatment groups. Imipramine exhibited significant improvement earlier in depressive symptoms, while viloxazine showed significant improvement earlier in anxious symptoms. The same frequency of treatment emergent symptoms occurred in the treatment groups. Premature termination as a consequence of adverse reactions was required in only 1 viloxazine and 1 placebo patient.

Duke Authors

Cited Authors

  • Petrie, WM; McEvoy, JP; Wilson, WH; Ban, TA; Guy, W

Published Date

  • 1980

Published In

Volume / Issue

  • 15 / 3

Start / End Page

  • 193 - 196

International Standard Serial Number (ISSN)

  • 0020-8272