A double-blind comparison of three dosages of flutroline (CP-36,584) in the treatment of schizophrenia
Publication
, Journal Article
McEvoy, JP; Berney, S; Wilson, WH; Ban, TA; Guy, W
Published in: International Pharmacopsychiatry
1980
Therapeutic and adverse effects of three dosages (1, 20 and 100 mg daily) of flutroline, a new γ-carboline with a preclinical pharmacological profile similar to active neuroleptic agents, were compared in a double-blind clinical trial in 25 newly-admitted schizophrenic patients. Therapeutic effects and extrapyramidal signs were seen at the 20 and 100-mg daily dosages, but not at the 1-mg dosage. Serum prolactin levels were significantly elevated only at the 100-mg daily dose.
Duke Scholars
Published In
International Pharmacopsychiatry
ISSN
0020-8272
Publication Date
1980
Volume
15
Issue
5
Start / End Page
318 / 324
Related Subject Headings
- Psychiatry
- 1702 Cognitive Sciences
- 1109 Neurosciences
- 1103 Clinical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
McEvoy, J. P., Berney, S., Wilson, W. H., Ban, T. A., & Guy, W. (1980). A double-blind comparison of three dosages of flutroline (CP-36,584) in the treatment of schizophrenia. International Pharmacopsychiatry, 15(5), 318–324.
McEvoy, J. P., S. Berney, W. H. Wilson, T. A. Ban, and W. Guy. “A double-blind comparison of three dosages of flutroline (CP-36,584) in the treatment of schizophrenia.” International Pharmacopsychiatry 15, no. 5 (1980): 318–24.
McEvoy JP, Berney S, Wilson WH, Ban TA, Guy W. A double-blind comparison of three dosages of flutroline (CP-36,584) in the treatment of schizophrenia. International Pharmacopsychiatry. 1980;15(5):318–24.
McEvoy, J. P., et al. “A double-blind comparison of three dosages of flutroline (CP-36,584) in the treatment of schizophrenia.” International Pharmacopsychiatry, vol. 15, no. 5, 1980, pp. 318–24.
McEvoy JP, Berney S, Wilson WH, Ban TA, Guy W. A double-blind comparison of three dosages of flutroline (CP-36,584) in the treatment of schizophrenia. International Pharmacopsychiatry. 1980;15(5):318–324.
Published In
International Pharmacopsychiatry
ISSN
0020-8272
Publication Date
1980
Volume
15
Issue
5
Start / End Page
318 / 324
Related Subject Headings
- Psychiatry
- 1702 Cognitive Sciences
- 1109 Neurosciences
- 1103 Clinical Sciences