Kindling: an animal model of complex partial epilepsy.

Journal Article (Journal Article)

Kindling is an animal model of complex partial epilepsy induced by focal electrical stimulation of the brain. This paper describes the phenomenon and underscores the limited nature of current insights into its basic mechanisms. Anatomical delineation of the underlying neural network is a necessary first step for elucidating the basic cellular and molecular mechanisms. Recent evidence suggests that the substantia nigra may be a crucial component of the network underlying limbic kindled seizures and possibly kindling itself.

Full Text

Duke Authors

Cited Authors

  • McNamara, JO

Published Date

  • 1984

Published In

Volume / Issue

  • 16 Suppl /

Start / End Page

  • S72 - S76

PubMed ID

  • 6095745

International Standard Serial Number (ISSN)

  • 0364-5134

Digital Object Identifier (DOI)

  • 10.1002/ana.410160712

Language

  • eng

Conference Location

  • United States