Spontaneous interictal spiking in the awake kindled rat.

Journal Article (Journal Article)

The spontaneous interictal spike (SIS) noted in EEG recordings is a signal of the abnormally excitable behavior of neurons in an epileptic focus. This study provides a detailed, quantitative, temporal and spatial profile of SIS in the amygdaloid kindled rat. The reproducible nature of the development and decline of SIS in kindling provides a useful model for biochemical study of the mechanisms that initiate and regulate SIS.

Full Text

Duke Authors

Cited Authors

  • Fitz, JG; McNamara, JO

Published Date

  • November 1, 1979

Published In

Volume / Issue

  • 47 / 5

Start / End Page

  • 592 - 596

PubMed ID

  • 91486

International Standard Serial Number (ISSN)

  • 0013-4694

Digital Object Identifier (DOI)

  • 10.1016/0013-4694(79)90260-8


  • eng

Conference Location

  • Ireland