Second malignancies in cutaneous T cell lymphoma.

Journal Article (Journal Article)

Among sixty-three cutaneous T cell lymphoma (CTCL) patients seen over a 15-year period at the Duke University Medical Center (DUMC), 15.9% had a second malignancy. This is a higher frequency of second malignancies than has been documented previously in any series of CTCL patients. We evaluated the incidence of subsequent primary malignancies in these CTCL patients by comparing our series of patients to a general population. The overall cancer incidence rate in the CTCL patients was 2.4 times, and in white male patients 3.3 times, greater than expected. We also compared various characteristics of CTCL patients with and without a second malignancy to evaluate potential predisposing factors. A history of prior chemotherapy and a family history of malignancy among first order relatives were more common among CTCL patients who developed a second malignancy.

Full Text

Duke Authors

Cited Authors

  • Olsen, EA; Delzell, E; Jegasothy, BV

Published Date

  • February 1, 1984

Published In

Volume / Issue

  • 10 / 2 Pt 1

Start / End Page

  • 197 - 204

PubMed ID

  • 6609176

Pubmed Central ID

  • 6609176

International Standard Serial Number (ISSN)

  • 0190-9622

Digital Object Identifier (DOI)

  • 10.1016/s0190-9622(84)70023-5


  • eng

Conference Location

  • United States