Journal Article (Journal Article;Review)

Cryptococcus neoformans has risen to a worldwide highly recognizable major opportunistic pathogen with deadly consequences. It has become a model fungus to study a variety of paradigms in the host-fungus relationships. Genomic studies are advancing knowledge on its evolution and dissecting its virulence composite. Studies designed to understand host immunology to this fungus are leading to development of active and passive prevention and therapeutic strategies. This article collates and analyzes both new and old knowledge about the pathogen to help frame the meaning of human cryptococcosis as it starts to evolve in the new millennium.

Full Text

Duke Authors

Cited Authors

  • Perfect, JR; Casadevall, A

Published Date

  • December 2002

Published In

Volume / Issue

  • 16 / 4

Start / End Page

  • 837 - vi

PubMed ID

  • 12512184

International Standard Serial Number (ISSN)

  • 0891-5520

Digital Object Identifier (DOI)

  • 10.1016/s0891-5520(02)00036-3


  • eng

Conference Location

  • United States