Incidence of death and MI associated with stopping clopidogrel after ACS


Journal Article

Rates of death and myocardial infarction were assessed for a national sample of acute coronary syndrome patients after stopping clopidogrel, in the first 90 days after stopping treatment, patients experienced a nearly twofold increased risk of adverse events compared with subsequent follow-up intervals for patients treated medically without stents and for patients treated with coronary stents. This suggests a possible clopidogrel rebound effect, but additional studies are needed to support this hypothesis and to identify strategies to reduce early events after clopidogrel cessation.

Duke Authors

Cited Authors

  • Ho, PM; Peterson, ED; Wang, L; Magid, DJ; Fihn, SD; Larsen, GC; Jesse, RA; Rumsfeld, JS

Published Date

  • October 1, 2008

Published In

Volume / Issue

  • 25 / 10

Start / End Page

  • 13 - 18

International Standard Serial Number (ISSN)

  • 1092-6607

Citation Source

  • Scopus