Oxygen toxicity.

Journal Article (Journal Article;Review)

That hyperoxia induces "a profound modification in the metabolism of tissues" is an old observation. The mechanisms by which the physiologic, pathologic, and biomechanical perturbations caused by oxygen relate to the in vivo manifestations of oxygen toxicity, however, have not been explained fully. This article reviews cellular mechanisms of toxicity, outlines the clinical manifestations of oxygen toxicity, and discusses methods of monitoring and modifying oxygen tolerance.

Full Text

Duke Authors

Cited Authors

  • Carraway, MS; Piantadosi, CA

Published Date

  • June 1999

Published In

Volume / Issue

  • 5 / 2

Start / End Page

  • 265 - 295

PubMed ID

  • 10333451

International Standard Serial Number (ISSN)

  • 1078-5337


  • eng

Conference Location

  • United States