Fluorescent probes that stain living nerve terminals.

Journal Article (Journal Article)

We have evaluated the efficacy of 18 cationic mitochondrial dyes that, as a class, show some ability to stain living nerve terminals. Several of these agents provide excellent staining of neuromuscular junctions in a wide range of species. More detailed studies of the most effective of these dyes--4-(4-diethylaminostyryl)-N-methylpyridinium iodide (4-Di-2-ASP)--indicate that it has no lasting effect on the structure or function of motor nerve terminals. As demonstrated in the accompanying paper (Lichtman et al., 1987; see also Lichtman et al., 1986), 4-Di-2-ASP can therefore be used to follow the configuration of identified motor terminals over arbitrarily long intervals.

Full Text

Duke Authors

Cited Authors

  • Magrassi, L; Purves, D; Lichtman, JW

Published Date

  • April 1, 1987

Published In

Volume / Issue

  • 7 / 4

Start / End Page

  • 1207 - 1214

PubMed ID

  • 3572476

Pubmed Central ID

  • PMC6568996

Electronic International Standard Serial Number (EISSN)

  • 1529-2401

International Standard Serial Number (ISSN)

  • 0270-6474

Digital Object Identifier (DOI)

  • 10.1523/jneurosci.07-04-01207.1987


  • eng