Enhanced affective aggression in genetically bred hypercholinergic rats.

Journal Article (Journal Article)

Affective aggression was studied in pairs of Flinders Sensitive Line hypercholinergic rats (FSL) and Flinders Resistant Line (FRL) rats in shock-induced and apomorphine-induced fighting tests. FSL rats were significantly more aggressive in both tests. They had higher pain threshold, assessed by the jump-flinch method, than FRL rats. It is concluded that genetically developed cholinergic system supersensitivity has resulted in enhanced responsiveness to stimuli eliciting affective aggression.

Full Text

Duke Authors

Cited Authors

  • Pucilowski, O; Eichelman, B; Overstreet, DH; Rezvani, AH; Janowsky, DS

Published Date

  • 1990

Published In

Volume / Issue

  • 24 / 1

Start / End Page

  • 37 - 41

PubMed ID

  • 2132639

International Standard Serial Number (ISSN)

  • 0302-282X

Digital Object Identifier (DOI)

  • 10.1159/000119040


  • eng

Conference Location

  • Switzerland