Impaired active avoidance responding in rats selectively bred for increased cholinergic function.
Journal Article (Journal Article)
It was found that the Flinders Sensitive Line (FSL) of rat, selectively bred for increased cholinergic function, performed poorly in a tone-cued two-way active avoidance task in comparison with the control Flinders Restraint Line (FRL) of rat. These findings are consistent with the suggestion that the FSL rats may be a genetic animal model of depression.
Full Text
Duke Authors
Cited Authors
- Overstreet, DH; Rezvani, AH; Janowsky, DS
Published Date
- April 1990
Published In
Volume / Issue
- 47 / 4
Start / End Page
- 787 - 788
PubMed ID
- 2385654
Pubmed Central ID
- 2385654
International Standard Serial Number (ISSN)
- 0031-9384
Digital Object Identifier (DOI)
- 10.1016/0031-9384(90)90097-n
Language
- eng
Conference Location
- United States