Skip to main content
Journal cover image

Long-term follow-up of patients with echocardiographically detected mitral anular calcium and comparison with age- and sex-matched control subjects.

Publication ,  Journal Article
Nair, CK; Thomson, W; Ryschon, K; Cook, C; Hee, TT; Sketch, MH
Published in: Am J Cardiol
February 15, 1989

One hundred seven patients with echocardiographically documented mitral anular calcium (MAC) and 107 age- and sex-matched control subjects without MAC were studied and followed for a mean of 4.4 +/- 2.4 (standard deviation) years. Fourteen (7%) patients were lost to follow-up. Compared with the control group, patients with MAC had higher frequency of precordial murmurs (p less than 0.0001), cardiomegaly (p less than 0.0001), left atrial enlargement (p less than 0.0001), and rhythm and conduction disturbances (p less than 0.0001). During the follow-up, patients with MAC had higher incidence of valve replacement (p less than 0.0025), permanent pacemaker implantation (p less than 0.0025), congestive heart failure (p less than 0.0001), thromboembolic cerebrovascular event (p less than 0.01), sudden death (p less than 0.001) and total cardiac death (p less than 0.0001). However, the frequencies of myocardial infarction, coronary artery bypass surgery and angioplasty, endocarditis or noncardiac death were not significantly different between patients with MAC and the control subjects. Thus, patients with MAC have higher frequencies of precordial murmurs, cardiomegaly, left atrial and ventricular enlargement, rhythm and conduction disturbances. They more frequently undergo valve replacement and permanent pacemaker implantation, develop congestive heart failure and die of cardiac causes than age- and sex-matched control subjects.

Duke Scholars

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

February 15, 1989

Volume

63

Issue

7

Start / End Page

465 / 470

Location

United States

Related Subject Headings

  • Mitral Valve
  • Middle Aged
  • Male
  • Humans
  • Heart Diseases
  • Follow-Up Studies
  • Female
  • Electrocardiography
  • Echocardiography
  • Cardiovascular System & Hematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Nair, C. K., Thomson, W., Ryschon, K., Cook, C., Hee, T. T., & Sketch, M. H. (1989). Long-term follow-up of patients with echocardiographically detected mitral anular calcium and comparison with age- and sex-matched control subjects. Am J Cardiol, 63(7), 465–470. https://doi.org/10.1016/0002-9149(89)90321-4
Nair, C. K., W. Thomson, K. Ryschon, C. Cook, T. T. Hee, and M. H. Sketch. “Long-term follow-up of patients with echocardiographically detected mitral anular calcium and comparison with age- and sex-matched control subjects.Am J Cardiol 63, no. 7 (February 15, 1989): 465–70. https://doi.org/10.1016/0002-9149(89)90321-4.
Nair CK, Thomson W, Ryschon K, Cook C, Hee TT, Sketch MH. Long-term follow-up of patients with echocardiographically detected mitral anular calcium and comparison with age- and sex-matched control subjects. Am J Cardiol. 1989 Feb 15;63(7):465–70.
Nair, C. K., et al. “Long-term follow-up of patients with echocardiographically detected mitral anular calcium and comparison with age- and sex-matched control subjects.Am J Cardiol, vol. 63, no. 7, Feb. 1989, pp. 465–70. Pubmed, doi:10.1016/0002-9149(89)90321-4.
Nair CK, Thomson W, Ryschon K, Cook C, Hee TT, Sketch MH. Long-term follow-up of patients with echocardiographically detected mitral anular calcium and comparison with age- and sex-matched control subjects. Am J Cardiol. 1989 Feb 15;63(7):465–470.
Journal cover image

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

February 15, 1989

Volume

63

Issue

7

Start / End Page

465 / 470

Location

United States

Related Subject Headings

  • Mitral Valve
  • Middle Aged
  • Male
  • Humans
  • Heart Diseases
  • Follow-Up Studies
  • Female
  • Electrocardiography
  • Echocardiography
  • Cardiovascular System & Hematology