Bone marrow-derived lymphoid cells (B cells): functional depletion with cobra factor and fresh serum.
Treatment of rat spleen cells with cobra factor and fresh rat serum provided a simple, rapid means of functionally eliminating complement receptor lymphocytes. Cells able to differentiate into plaque-forming cells in a syngeneic, irradiated host were diminished, but cells able to induce a graft-versus-host reaction were not diminished. There was no effect on plaque-forming cells from an immune spleen.
Levy, NL; Scott, DW; Snyderman, R
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