Chemotactic and anaphylatoxic fragment cleaved from the fifth component of guinea pig complement.
Publication
, Journal Article
Shin, HS; Snyderman, R; Friedman, E; Mellors, A; Mayer, MM
Published in: Science
October 18, 1968
The fifth component of guinea pig complement, with a sedimentation coefficient 7.8S, is cleaved by sensitized sheep erythrocytes treated with the first four components of complement into two fragments with sedimentation coefficients of 7.4S and 1.5S. The smaller fragment, with a molecular weight of about 15,000, possesses chemotactic activity for rabbit polymorphonuclear leukocytes, as well as anaphylatoxic activity for guinea pig ileum.
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Published In
Science
DOI
ISSN
0036-8075
Publication Date
October 18, 1968
Volume
162
Issue
3851
Start / End Page
361 / 363
Location
United States
Related Subject Headings
- Toxins, Biological
- Sheep
- Rabbits
- Neutrophils
- Molecular Weight
- Inflammation
- Ileum
- Guinea Pigs
- General Science & Technology
- Erythrocytes
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NLM
Shin, H. S., Snyderman, R., Friedman, E., Mellors, A., & Mayer, M. M. (1968). Chemotactic and anaphylatoxic fragment cleaved from the fifth component of guinea pig complement. Science, 162(3851), 361–363. https://doi.org/10.1126/science.162.3851.361
Shin, H. S., R. Snyderman, E. Friedman, A. Mellors, and M. M. Mayer. “Chemotactic and anaphylatoxic fragment cleaved from the fifth component of guinea pig complement.” Science 162, no. 3851 (October 18, 1968): 361–63. https://doi.org/10.1126/science.162.3851.361.
Shin HS, Snyderman R, Friedman E, Mellors A, Mayer MM. Chemotactic and anaphylatoxic fragment cleaved from the fifth component of guinea pig complement. Science. 1968 Oct 18;162(3851):361–3.
Shin, H. S., et al. “Chemotactic and anaphylatoxic fragment cleaved from the fifth component of guinea pig complement.” Science, vol. 162, no. 3851, Oct. 1968, pp. 361–63. Pubmed, doi:10.1126/science.162.3851.361.
Shin HS, Snyderman R, Friedman E, Mellors A, Mayer MM. Chemotactic and anaphylatoxic fragment cleaved from the fifth component of guinea pig complement. Science. 1968 Oct 18;162(3851):361–363.
Published In
Science
DOI
ISSN
0036-8075
Publication Date
October 18, 1968
Volume
162
Issue
3851
Start / End Page
361 / 363
Location
United States
Related Subject Headings
- Toxins, Biological
- Sheep
- Rabbits
- Neutrophils
- Molecular Weight
- Inflammation
- Ileum
- Guinea Pigs
- General Science & Technology
- Erythrocytes