Deep venous thrombosis and a circulating anticoagulant in systemic lupus erythematosus.

Journal Article (Journal Article)

We describe deep venous thrombosis and a circulating anticoagulant in a male adolescent with systemic lupus erythematosus (SLE). The association of deep vein thrombosis with SLE in a pediatric patient has not, to our knowledge, been previously reported. The circulating anticoagulant was characterized as a lupus-type inhibitor. This was demonstrated by an abnormal partial thromboplastin time (PTT), the failure of the PTT to correct with the addition of an equal amount of normal plasma, and a positive tissue thromboplastin inhibitor test. Physicians should be aware that a circulating anticoagulant can be associated with SLE and that there may be a paradoxically increased incidence of thromboembolic phenomena in patients with this abnormality.

Full Text

Duke Authors

Cited Authors

  • St Clair, W; Jones, B; Rogers, JS; Crouch, M; Hrabovsky, E

Published Date

  • March 1, 1981

Published In

Volume / Issue

  • 135 / 3

Start / End Page

  • 230 - 232

PubMed ID

  • 7211777

International Standard Serial Number (ISSN)

  • 0002-922X

Digital Object Identifier (DOI)

  • 10.1001/archpedi.1981.02130270022008


  • eng

Conference Location

  • United States