Hippocampal volume as a predictor of short-term ECT outcomes in older patients with depression.

Journal Article (Journal Article)

OBJECTIVE: The authors examined the relationship between hippocampal volume and acute electroconvulsive therapy (ECT) outcomes. METHODS: Depression was measured by Montgomery-Asberg Depression Rating Scale (MADRS) scores, and hippocampal volume was assessed by magnetic resonance imaging. RESULTS: After controlling for baseline MADRS score, larger right-hippocampal volume was associated with higher MADRS scores after an index course of ECT. CONCLUSION: These results are the converse of those obtained in a study assessing the relationship between hippocampal volume and pharmacotherapy. The findings suggest a need for further study in this area.

Full Text

Duke Authors

Cited Authors

  • Lekwauwa, RE; McQuoid, DR; Steffens, DC

Published Date

  • October 2005

Published In

Volume / Issue

  • 13 / 10

Start / End Page

  • 910 - 913

PubMed ID

  • 16223970

International Standard Serial Number (ISSN)

  • 1064-7481

Digital Object Identifier (DOI)

  • 10.1176/appi.ajgp.13.10.910


  • eng

Conference Location

  • England